Volume-sensitive outwardly rectifying chloride channel blockers protect against high glucose-induced apoptosis of cardiomyocytes via autophagy activation

Hyperglycemia is a well-characterized contributing factor for cardiac dysfunction and heart failure among diabetic patients. Apoptosis of cardiomyocytes plays a major role during the onset and pathogenesis of diabetic cardiomyopathy (DCM). Nonetheless, the molecular machinery underlying hyperglycemi...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Shen, Mingzhi, Guo, Xiaowang, Wang, Bo, Xia, Yuesheng, Wang, Ning, Zhang, Qian, Jia, Lintao, Wang, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353972/
https://www.ncbi.nlm.nih.gov/pubmed/28300155
http://dx.doi.org/10.1038/srep44265

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