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Recurrent Obstructive Fibrinous Tracheal Pseudomembranes in a Young English Bulldog

Endotracheal intubation is a common procedure, rarely associated with life‐threatening complications (e.g., tracheal rupture, necrosis, foreign body). A 1.5‐year‐old English Bulldog was presented for respiratory distress, with increased respiratory efforts and stridor, 2 days after endotracheal intu...

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Detalles Bibliográficos
Autores principales: Robin, E., Guieu, L.V., Le Boedec, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354013/
https://www.ncbi.nlm.nih.gov/pubmed/28224661
http://dx.doi.org/10.1111/jvim.14650
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author Robin, E.
Guieu, L.V.
Le Boedec, K.
author_facet Robin, E.
Guieu, L.V.
Le Boedec, K.
author_sort Robin, E.
collection PubMed
description Endotracheal intubation is a common procedure, rarely associated with life‐threatening complications (e.g., tracheal rupture, necrosis, foreign body). A 1.5‐year‐old English Bulldog was presented for respiratory distress, with increased respiratory efforts and stridor, 2 days after endotracheal intubation. Cervical and thoracic radiographs disclosed a severe narrowing of the tracheal lumen associated with an intraluminal soft‐tissue structure at the thoracic inlet. Tracheoscopy confirmed the presence of an obstructive fibrinous tracheal pseudomembrane (OFTP) creating a 1‐way valve obstruction. Removal of the OFTP dramatically improved the dog's respiratory function, but the lesion reformed twice despite corticosteroid and antibiotic therapy PO, warranting repeated endoscopic removal of the OFTP. No additional recurrences were observed after treatment with inhaled heparin and N‐acetylcysteine q4h. No respiratory signs were reported 9 months after discharge. Postintubation OFTP has been reported rarely in humans and never described in dogs. Unexplained signs of upper airway obstruction shortly after endotracheal intubation should prompt consideration of OFTP in dogs, even if intubation was uneventful. Unlike its counterpart in humans, OFTP in dogs can reoccur after endoscopic removal, warranting repeated endoscopic extraction. A combination of corticosteroid therapy PO and heparin and N‐acetylcysteine inhalation q4h may be attempted if recurrence is observed.
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spelling pubmed-53540132017-03-22 Recurrent Obstructive Fibrinous Tracheal Pseudomembranes in a Young English Bulldog Robin, E. Guieu, L.V. Le Boedec, K. J Vet Intern Med SMALL ANIMAL Endotracheal intubation is a common procedure, rarely associated with life‐threatening complications (e.g., tracheal rupture, necrosis, foreign body). A 1.5‐year‐old English Bulldog was presented for respiratory distress, with increased respiratory efforts and stridor, 2 days after endotracheal intubation. Cervical and thoracic radiographs disclosed a severe narrowing of the tracheal lumen associated with an intraluminal soft‐tissue structure at the thoracic inlet. Tracheoscopy confirmed the presence of an obstructive fibrinous tracheal pseudomembrane (OFTP) creating a 1‐way valve obstruction. Removal of the OFTP dramatically improved the dog's respiratory function, but the lesion reformed twice despite corticosteroid and antibiotic therapy PO, warranting repeated endoscopic removal of the OFTP. No additional recurrences were observed after treatment with inhaled heparin and N‐acetylcysteine q4h. No respiratory signs were reported 9 months after discharge. Postintubation OFTP has been reported rarely in humans and never described in dogs. Unexplained signs of upper airway obstruction shortly after endotracheal intubation should prompt consideration of OFTP in dogs, even if intubation was uneventful. Unlike its counterpart in humans, OFTP in dogs can reoccur after endoscopic removal, warranting repeated endoscopic extraction. A combination of corticosteroid therapy PO and heparin and N‐acetylcysteine inhalation q4h may be attempted if recurrence is observed. John Wiley and Sons Inc. 2017-02-22 2017 /pmc/articles/PMC5354013/ /pubmed/28224661 http://dx.doi.org/10.1111/jvim.14650 Text en Copyright © 2017 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle SMALL ANIMAL
Robin, E.
Guieu, L.V.
Le Boedec, K.
Recurrent Obstructive Fibrinous Tracheal Pseudomembranes in a Young English Bulldog
title Recurrent Obstructive Fibrinous Tracheal Pseudomembranes in a Young English Bulldog
title_full Recurrent Obstructive Fibrinous Tracheal Pseudomembranes in a Young English Bulldog
title_fullStr Recurrent Obstructive Fibrinous Tracheal Pseudomembranes in a Young English Bulldog
title_full_unstemmed Recurrent Obstructive Fibrinous Tracheal Pseudomembranes in a Young English Bulldog
title_short Recurrent Obstructive Fibrinous Tracheal Pseudomembranes in a Young English Bulldog
title_sort recurrent obstructive fibrinous tracheal pseudomembranes in a young english bulldog
topic SMALL ANIMAL
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354013/
https://www.ncbi.nlm.nih.gov/pubmed/28224661
http://dx.doi.org/10.1111/jvim.14650
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