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Epidermal loss of Gα(q) confers a migratory and differentiation defect in keratinocytes
G-protein coupled receptors (GPCRs), which activate heterotrimeric G proteins, are an essential class of transmembrane receptors that are responsible for a myriad of signaling events in normal and pathologic conditions. Two members of the G protein family, Gα(q) and Gα(11), activate one of the main...
Autores principales: | Doçi, Colleen L., Mikelis, Constantinos M., Callejas-Valera, Juan Luis, Hansen, Karina K., Molinolo, Alfredo A., Inoue, Asuka, Offermanns, Stefan, Gutkind, J. Silvio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354386/ https://www.ncbi.nlm.nih.gov/pubmed/28301547 http://dx.doi.org/10.1371/journal.pone.0173692 |
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