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Daxx plays a novel role in T cell survival but is dispensable in Fas-induced apoptosis
Daxx was originally isolated as a Fas-binding protein. However, the in vivo function of Daxx in Fas-induced apoptosis has remained enigmatic. Fas plays an important role in homeostasis in the immune system. Fas gene mutations lead to autoimmune-lymphoproliferation (lpr) diseases characterized by hyp...
Autores principales: | Li, Jinghe, Qian, Liangyue, Dowling, John P., Curcione, Christine, Kurup, Drishya, Zhang, Jianke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354431/ https://www.ncbi.nlm.nih.gov/pubmed/28301594 http://dx.doi.org/10.1371/journal.pone.0174011 |
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