TASK-1 potassium channel is not critically involved in mediating hypoxic pulmonary vasoconstriction of murine intra-pulmonary arteries

The two-pore domain potassium channel KCNK3 (TASK-1) is expressed in rat and human pulmonary artery smooth muscle cells. There, it is associated with hypoxia-induced signalling, and its dysfunction is linked to pathogenesis of human pulmonary hypertension. We here aimed to determine its role in hypo...

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Detalles Bibliográficos
Autores principales: Murtaza, Ghulam, Mermer, Petra, Goldenberg, Anna, Pfeil, Uwe, Paddenberg, Renate, Weissmann, Nobert, Lochnit, Guenter, Kummer, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354433/
https://www.ncbi.nlm.nih.gov/pubmed/28301582
http://dx.doi.org/10.1371/journal.pone.0174071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354433/
https://www.ncbi.nlm.nih.gov/pubmed/28301582
http://dx.doi.org/10.1371/journal.pone.0174071

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