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GTL001, a bivalent therapeutic vaccine against human papillomavirus 16 and 18, induces antigen-specific CD8(+) T cell responses leading to tumor regression

BACKGROUND: Prophylactic vaccines are available for women and girls not yet infected with HPV, but women already infected with HPV need a treatment to prevent progression to high-grade cervical lesions and cancer. GTL001 is a bivalent therapeutic vaccine for eradicating HPV-infected cells that conta...

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Detalles Bibliográficos
Autores principales:	Esquerré, Michaël, Bouillette-Marussig, Myriam, Goubier, Anne, Momot, Marie, Gonindard, Christophe, Keller, Hélène, Navarro, Astrid, Bissery, Marie-Christine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354464/ https://www.ncbi.nlm.nih.gov/pubmed/28301611 http://dx.doi.org/10.1371/journal.pone.0174038

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