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A maternal high-fat, high-sucrose diet has sex-specific effects on fetal glucocorticoids with little consequence for offspring metabolism and voluntary locomotor activity in mice

Maternal overnutrition and obesity during pregnancy can have long-term effects on offspring physiology and behaviour. These developmental programming effects may be mediated by fetal exposure to glucocorticoids, which is regulated in part by placental 11β-hydroxysteroid dehydrogenase (11β-HSD) type...

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Detalles Bibliográficos
Autores principales: Chin, Eunice H., Schmidt, Kim L., Martel, Kaitlyn M., Wong, Chi Kin, Hamden, Jordan E., Gibson, William T., Soma, Kiran K., Christians, Julian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354465/
https://www.ncbi.nlm.nih.gov/pubmed/28301585
http://dx.doi.org/10.1371/journal.pone.0174030