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Cyclic RGD peptide-modified liposomal drug delivery system for targeted oral apatinib administration: enhanced cellular uptake and improved therapeutic effects

Apatinib is an oral tyrosine kinase inhibitor, which selectively targets vascular endothelial growth factor receptor 2 and has the potential to treat many tumors therapeutically. Cyclic arginylglycylaspartic acid (cRGD)- and polyethylene glycol (PEG)-modified liposomes (cRGD-Lipo-PEG) were construct...

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Detalles Bibliográficos
Autores principales:	Song, Zhiwang, Lin, Yun, Zhang, Xia, Feng, Chan, Lu, Yonglin, Gao, Yong, Dong, Chunyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354530/ https://www.ncbi.nlm.nih.gov/pubmed/28331317 http://dx.doi.org/10.2147/IJN.S125573

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