Polymorphisms in genes TLR1, 2 and 4 are associated with differential cytokine and chemokine serum production in patients with leprosy

BACKGROUND: Leprosy or hansen’s disease is a spectral disease whose clinical forms mostly depends on host’s immune and genetic factors. Different Toll-like receptors (TLR) variants have been described associated with leprosy, but with some lack of replication across different populations. OBJECTIVES...

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Autores principales: Santana, Nadja de Lima, Rêgo, Jamile Leão, Oliveira, Joyce Moura, de Almeida, Lucas Frederico, Braz, Marcos, Machado, Lídia Maria Medeiros, Machado, Paulo Roberto Lima, Castellucci, Léa Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354609/
https://www.ncbi.nlm.nih.gov/pubmed/28327786
http://dx.doi.org/10.1590/0074-02760160366

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