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Spermatogonial stem cells and progenitors are refractory to reprogramming to pluripotency by the transcription factors Oct3/4, c-Myc, Sox2 and Klf4

The male germinal lineage, which is defined as unipotent, produces sperm through spermatogenesis. However, embryonic primordial germ cells and postnatal spermatogonial stem cells (SSCs) can change their fate and convert to pluripotency in culture when they are not controlled by the testicular microe...

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Detalles Bibliográficos
Autores principales: Corbineau, Sébastien, Lassalle, Bruno, Givelet, Maelle, Souissi-Sarahoui, Inès, Firlej, Virginie, Romeo, Paul Henri, Allemand, Isabelle, Riou, Lydia, Fouchet, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354640/
https://www.ncbi.nlm.nih.gov/pubmed/28052023
http://dx.doi.org/10.18632/oncotarget.14327

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