Opposing roles of PIK3CA gene alterations to EZH2 signaling in non-muscle invasive bladder cancer

The high rates of tumor recurrence and progression represent a major clinical problem in non-muscle invasive bladder cancer. Previous data showed that EZH2-dependent signaling mediates these processes, whereas the frequent alterations of PIK3CA gene (copy gains and mutations) are predictive of reduc...

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Detalles Bibliográficos
Autores principales: Segovia, Cristina, Martínez-Fernández, Mónica, Dueñas, Marta, Rubio, Carolina, López-Calderón, Fernando F., Costa, Clotilde, Saiz-Ladera, Cristina, Fernández-Grajera, María, Duarte, José, García Muñoz, Huberto, de la Rosa, Federico, Villacampa, Felipe, Castellano, Daniel, Paramio, Jesús M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354678/
https://www.ncbi.nlm.nih.gov/pubmed/28060766
http://dx.doi.org/10.18632/oncotarget.14453

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