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Targeted activation of AMPK by GSK621 ameliorates H(2)O(2)-induced damages in osteoblasts

GSK621 is a novel AMP-activated protein kinase (AMPK) activator. This study tested its potential cytoprotective effect in hydrogen peroxide (H(2)O(2))-treated osteoblasts. In cultured MC3T3-E1 osteoblastic cells and primary murine osteoblasts, GSK621 significantly attenuated H(2)O(2)-induced cell de...

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Detalles Bibliográficos
Autores principales:	Liu, Weidong, Mao, Li, Ji, Feng, Chen, Fengli, Hao, Yuedong, Liu, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354679/ https://www.ncbi.nlm.nih.gov/pubmed/28060740 http://dx.doi.org/10.18632/oncotarget.14454

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