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Metformin: a metabolic modulator
Recent findings have shed new light on the mechanisms of action through which biguanides exert their anti-aging and cytostatic effects in Caenorhabditis elegans and human cell lines. The drop in energy charge resulting from the metformin mediated inhibition of mitochondrial activity affects the func...
Autores principales: | Pietrocola, Federico, Kroemer, Guido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354711/ https://www.ncbi.nlm.nih.gov/pubmed/28122334 http://dx.doi.org/10.18632/oncotarget.14794 |
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