Loss of RUNX3 expression inhibits bone invasion of oral squamous cell carcinoma

High recurrence and lower survival rates in patients with oral squamous cell carcinoma (OSCC) are associated with its bone invasion. We identified the oncogenic role of RUNX3 during bone invasion by OSCC. Tumor growth and the generation of osteolytic lesions were significantly inhibited in mice that...

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Detalles Bibliográficos
Autores principales: Park, Junhee, Kim, Hyun-Jeong, Kim, Ki Rim, Lee, Sun Kyoung, Kim, Hyungkeun, Park, Kwang-Kyun, Chung, Won-Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354716/
https://www.ncbi.nlm.nih.gov/pubmed/28030842
http://dx.doi.org/10.18632/oncotarget.14071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354716/
https://www.ncbi.nlm.nih.gov/pubmed/28030842
http://dx.doi.org/10.18632/oncotarget.14071

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