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Reducing Smad3/ATF4 was essential for Sirt1 inhibiting ER stress-induced apoptosis in mice brown adipose tissue

Sirtuin 1 (Sirt1) promotes adaptive thermogenesis by controlling the acetylation status of enzymes and transcriptional factors in interscapular brown adipose tissue (iBAT). However, the effects of Sirt1 on endoplasmic reticulum (ER) stress and apoptosis of iBAT remain elusive. In this study, the mRN...

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Detalles Bibliográficos
Autores principales:	Liu, Zhenjiang, Gu, Huihui, Gan, Lu, Xu, Yatao, Feng, Fei, Saeed, Muhammad, Sun, Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354730/ https://www.ncbi.nlm.nih.gov/pubmed/28030827 http://dx.doi.org/10.18632/oncotarget.14035

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