Vamorolone, a dissociative steroidal compound, reduces pro-inflammatory cytokine expression in glioma cells and increases activity and survival in a murine model of cortical tumor

Corticosteroids, such as dexamethasone, are routinely used as palliative care in neuro-oncology for their anti-inflammatory benefits, however many patients experience dose limiting side effects caused by glucocorticoid response element (GRE)-mediated transcription. The purpose of this study was to u...

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Detalles Bibliográficos
Autores principales: Wells, Elizabeth, Kambhampati, Madhuri, Damsker, Jesse M, Gordish-Dressman, Heather, Yadavilli, Sridevi, Becher, Oren J, Gittens, Jamila, Stampar, Mojca, Packer, Roger J, Nazarian, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354737/
https://www.ncbi.nlm.nih.gov/pubmed/28030841
http://dx.doi.org/10.18632/oncotarget.14070

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