Chimeric antigen receptor-modified T Cells inhibit the growth and metastases of established tissue factor-positive tumors in NOG mice

Chimeric antigen receptor (CAR)-modified T cell (CAR T) is a promising therapeutic option for patients with cancer. Such an approach requires the identification of tumor-specific antigen targets that are expressed in solid tumors. We developed a new third-generation CAR directed against tissue facto...

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Detalles Bibliográficos
Autores principales: Zhang, Qing, Wang, Haiyu, Li, Huizhong, Xu, Jinjing, Tian, Kang, Yang, Jie, Lu, Zheng, Zheng, Junnian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354747/
https://www.ncbi.nlm.nih.gov/pubmed/28055955
http://dx.doi.org/10.18632/oncotarget.14367

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