Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer

Clinical studies in breast cancer suggest important associations between intratumoral hypoxia, the upregulation of epidermal growth factor receptor (EGFR or HER1), hypoxia-inducible factor 1α (HIF-1α), and reduced patient survival. However, direct molecular links between EGFR and the hypoxia signali...

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Detalles Bibliográficos
Autores principales: Kozlova, Nina, Wottawa, Marieke, Katschinski, Dörthe Magdalena, Kristiansen, Glen, Kietzmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354778/
https://www.ncbi.nlm.nih.gov/pubmed/28038470
http://dx.doi.org/10.18632/oncotarget.14241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354778/
https://www.ncbi.nlm.nih.gov/pubmed/28038470
http://dx.doi.org/10.18632/oncotarget.14241

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