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Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer
Clinical studies in breast cancer suggest important associations between intratumoral hypoxia, the upregulation of epidermal growth factor receptor (EGFR or HER1), hypoxia-inducible factor 1α (HIF-1α), and reduced patient survival. However, direct molecular links between EGFR and the hypoxia signali...
Autores principales: | Kozlova, Nina, Wottawa, Marieke, Katschinski, Dörthe Magdalena, Kristiansen, Glen, Kietzmann, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354778/ https://www.ncbi.nlm.nih.gov/pubmed/28038470 http://dx.doi.org/10.18632/oncotarget.14241 |
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