Antagonism of Interleukin-17A ameliorates experimental hepatic fibrosis by restoring the IL-10/STAT3-suppressed autophagy in hepatocytes

Interleukin-17A has been identified as a driver of hepatic stellate cell activation and plays a critical role in the pathogenesis of hepatic fibrosis. However, the underlining fibrosis-promoting mechanism of IL-17A is far from understood. Here we aimed to define whether hepatocytes directly respond...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Wei, Mi, Su, Li, Zhe, Zhou, Ji-Chao, Xie, Jing, Hua, Fang, Li, Ke, Cui, Bing, Lv, Xiao-Xi, Yu, Jiao-Jiao, Hu, Zhuo-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354781/
https://www.ncbi.nlm.nih.gov/pubmed/28039485
http://dx.doi.org/10.18632/oncotarget.14266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354781/
https://www.ncbi.nlm.nih.gov/pubmed/28039485
http://dx.doi.org/10.18632/oncotarget.14266

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