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Antagonism of Interleukin-17A ameliorates experimental hepatic fibrosis by restoring the IL-10/STAT3-suppressed autophagy in hepatocytes
Interleukin-17A has been identified as a driver of hepatic stellate cell activation and plays a critical role in the pathogenesis of hepatic fibrosis. However, the underlining fibrosis-promoting mechanism of IL-17A is far from understood. Here we aimed to define whether hepatocytes directly respond...
Autores principales: | Zhang, Xiao-Wei, Mi, Su, Li, Zhe, Zhou, Ji-Chao, Xie, Jing, Hua, Fang, Li, Ke, Cui, Bing, Lv, Xiao-Xi, Yu, Jiao-Jiao, Hu, Zhuo-Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354781/ https://www.ncbi.nlm.nih.gov/pubmed/28039485 http://dx.doi.org/10.18632/oncotarget.14266 |
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