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Signaling regulation and role of filamin A cleavage in Ca(2+)-stimulated migration of androgen receptor-deficient prostate cancer cells

Ca(2+), a ubiquitous cellular signal, and filamin A, an actin-binding protein, play an important role in the regulation of cell adhesion, shape and motility. Using transwell filters to analyze cell migration, we found that extracellular Ca(2+) (Ca(o)(2+)) promotes the migration of androgen receptor...

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Detalles Bibliográficos
Autores principales: Huang, Chunfa, Tyler Miller, R., Freter, Carl E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354799/
https://www.ncbi.nlm.nih.gov/pubmed/27206800
http://dx.doi.org/10.18632/oncotarget.9472