Sex chromosome abnormalities and psychiatric diseases

Excesses of sex chromosome abnormalities in patients with psychiatric diseases have recently been observed. It remains unclear whether sex chromosome abnormalities are related to sex differences in some psychiatric diseases. While studies showed evidence of susceptibility loci over many sex chromoso...

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Detalles Bibliográficos
Autores principales: Zhang, Xinzhu, Yang, Jian, Li, Yuhong, Ma, Xin, Li, Rena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354807/
https://www.ncbi.nlm.nih.gov/pubmed/27992373
http://dx.doi.org/10.18632/oncotarget.13962
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author Zhang, Xinzhu
Yang, Jian
Li, Yuhong
Ma, Xin
Li, Rena
author_facet Zhang, Xinzhu
Yang, Jian
Li, Yuhong
Ma, Xin
Li, Rena
author_sort Zhang, Xinzhu
collection PubMed
description Excesses of sex chromosome abnormalities in patients with psychiatric diseases have recently been observed. It remains unclear whether sex chromosome abnormalities are related to sex differences in some psychiatric diseases. While studies showed evidence of susceptibility loci over many sex chromosomal regions related to various mental diseases, others demonstrated that the sex chromosome aneuploidies may be the key to exploring the pathogenesis of psychiatric disease. In this review, we will outline the current evidence on the interaction of sex chromosome abnormalities with schizophrenia, autism, ADHD and mood disorders.
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spelling pubmed-53548072017-04-24 Sex chromosome abnormalities and psychiatric diseases Zhang, Xinzhu Yang, Jian Li, Yuhong Ma, Xin Li, Rena Oncotarget Research Paper Excesses of sex chromosome abnormalities in patients with psychiatric diseases have recently been observed. It remains unclear whether sex chromosome abnormalities are related to sex differences in some psychiatric diseases. While studies showed evidence of susceptibility loci over many sex chromosomal regions related to various mental diseases, others demonstrated that the sex chromosome aneuploidies may be the key to exploring the pathogenesis of psychiatric disease. In this review, we will outline the current evidence on the interaction of sex chromosome abnormalities with schizophrenia, autism, ADHD and mood disorders. Impact Journals LLC 2016-12-15 /pmc/articles/PMC5354807/ /pubmed/27992373 http://dx.doi.org/10.18632/oncotarget.13962 Text en Copyright: © 2017 Zhang et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Paper
Zhang, Xinzhu
Yang, Jian
Li, Yuhong
Ma, Xin
Li, Rena
Sex chromosome abnormalities and psychiatric diseases
title Sex chromosome abnormalities and psychiatric diseases
title_full Sex chromosome abnormalities and psychiatric diseases
title_fullStr Sex chromosome abnormalities and psychiatric diseases
title_full_unstemmed Sex chromosome abnormalities and psychiatric diseases
title_short Sex chromosome abnormalities and psychiatric diseases
title_sort sex chromosome abnormalities and psychiatric diseases
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354807/
https://www.ncbi.nlm.nih.gov/pubmed/27992373
http://dx.doi.org/10.18632/oncotarget.13962
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AT liyuhong sexchromosomeabnormalitiesandpsychiatricdiseases
AT maxin sexchromosomeabnormalitiesandpsychiatricdiseases
AT lirena sexchromosomeabnormalitiesandpsychiatricdiseases

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