Cargando…

Isochaihulactone-induced DDIT3 causes ER stress-PERK independent apoptosis in glioblastoma multiforme cells

The endoplasmic reticulum (ER) is a major site of cellular homeostasis regulation. Under the ER stress condition, Glioblastoma multiform (GBM) cells activate the unfolded protein response. In this study, we discovered isochaihulactone, a natural compound extracted from the Chinese traditional herb N...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsai, Sheng-Feng, Tao, Michael, Ho, Li-Ing, Chiou, Tzyy-Wen, Lin, Shinn-Zong, Su, Hong-Lin, Harn, Horng-Jyh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354812/
https://www.ncbi.nlm.nih.gov/pubmed/27852055
http://dx.doi.org/10.18632/oncotarget.13266