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Andrographolide impedes cancer stemness and enhances radio-sensitivity in oral carcinomas via miR-218 activation
Current evidence suggests that oral cancer stem cells (OCSCs) possess high tumorigenic and metastatic properties as well as chemo- and radioresistance. In this study, we demonstrated that andrographolide, the main bioactive component in the medicinal plant Andrographis, significantly reduced oncogen...
Autores principales: | Yang, Po-Yu, Hsieh, Pei-Ling, Wang, Tong Hong, Yu, Cheng-Chia, Lu, Ming-Yi, Liao, Yi-Wen, Lee, Tzu-Hsin, Peng, Chih-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354823/ https://www.ncbi.nlm.nih.gov/pubmed/27926533 http://dx.doi.org/10.18632/oncotarget.13755 |
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