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Autocrine IL-6 mediates pituitary tumor senescence
Cellular senescence is a stable proliferative arrest state. Pituitary adenomas are frequent and mostly benign, but the mechanism for this remains unknown. IL-6 is involved in pituitary tumor progression and is produced by the tumoral cells. In a cell autonomous fashion, IL-6 participates in oncogene...
Autores principales: | Sapochnik, Melanie, Haedo, Mariana R, Fuertes, Mariana, Ajler, Pablo, Carrizo, Guillermo, Cervio, Andrés, Sevlever, Gustavo, Stalla, Günter K., Arzt, Eduardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354864/ https://www.ncbi.nlm.nih.gov/pubmed/27902467 http://dx.doi.org/10.18632/oncotarget.13577 |
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