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CDH1 regulates E2F1 degradation in response to differentiation signals in keratinocytes

The E2F1 transcription factor plays key roles in skin homeostasis. In the epidermis, E2F1 expression is essential for normal proliferation of undifferentiated keratinocytes, regeneration after injury and DNA repair following UV radiation-induced photodamage. Abnormal E2F1 expression promotes nonmela...

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Detalles Bibliográficos
Autores principales: Singh, Randeep K., Dagnino, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354885/
https://www.ncbi.nlm.nih.gov/pubmed/27903963
http://dx.doi.org/10.18632/oncotarget.13636