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Mael is essential for cancer cell survival and tumorigenesis through protection of genetic integrity

Germ line-specific genes are activated in somatic cells during tumorigenesis, and are accordingly referred to as cancer germline genes. Such genes that act on piRNA (Piwi-interacting RNA) processing play an important role in the progression of cancer cells. Here, we show that the spermatogenic trans...

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Detalles Bibliográficos
Autores principales: Kim, Su-Hyeon, Park, Eun-Ran, Cho, Eugene, Jung, Won-Hee, Jeon, Ju-Yeon, Joo, Hyun-Yoo, Lee, Kee-Ho, Shin, Hyun-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354889/
https://www.ncbi.nlm.nih.gov/pubmed/27926513
http://dx.doi.org/10.18632/oncotarget.13756

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