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FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway

Forkhead box D3 (FOXD3), as a transcriptional repressor, is well known to be involved in the regulation of development. Although FoxD3 is associated with several cancers, its role in colon cancer and the underlying mechanism are still unclear. Here, we first showed that FOXD3 knockdown dramatically...

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Detalles Bibliográficos
Autores principales: Li, Kun, Guo, Qunfeng, Yang, Jun, Chen, Hui, Hu, Kewen, Zhao, Juan, Zheng, Shunxin, Pang, Xiufeng, Zhou, Sufang, Dang, Yongyan, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354891/
https://www.ncbi.nlm.nih.gov/pubmed/27926503
http://dx.doi.org/10.18632/oncotarget.13790