High throughput estimation of functional cell activities reveals disease mechanisms and predicts relevant clinical outcomes

Understanding the aspects of the cell functionality that account for disease or drug action mechanisms is a main challenge for precision medicine. Here we propose a new method that models cell signaling using biological knowledge on signal transduction. The method recodes individual gene expression...

Descripción completa

Detalles Bibliográficos
Autores principales: Hidalgo, Marta R., Cubuk, Cankut, Amadoz, Alicia, Salavert, Francisco, Carbonell-Caballero, José, Dopazo, Joaquin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354899/
https://www.ncbi.nlm.nih.gov/pubmed/28042959
http://dx.doi.org/10.18632/oncotarget.14107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354899/
https://www.ncbi.nlm.nih.gov/pubmed/28042959
http://dx.doi.org/10.18632/oncotarget.14107

Ejemplares similares