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Antitumor effect of an adeno-associated virus expressing apolipoprotein A-1 fused to interferon alpha in an interferon alpha-resistant murine tumor model
Interferon alpha (IFNα) is a cytokine approved for the treatment of several types of cancer. However, the modest effect on overall survival and the high toxicity associated with the treatment has reduced the clinical use of this cytokine. In this study, we have developed a tumor model that reproduce...
Autores principales: | Vasquez, Marcos, Paredes-Cervantes, Vladimir, Aranda, Fernando, Ardaiz, Nuria, Gomar, Celia, Berraondo, Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354905/ https://www.ncbi.nlm.nih.gov/pubmed/28029653 http://dx.doi.org/10.18632/oncotarget.14127 |
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