Cargando…
Targeting the VEGF-C/VEGFR3 axis suppresses Slug-mediated cancer metastasis and stemness via inhibition of KRAS/YAP1 signaling
Vascular endothelial growth factor-C (VEGF-C) has been implicated in epithelial-mesenchymal transition (EMT) processes and various human cancers, including skin cancer. Skin cancer is an aggressive human malignancy with increasing incidence worldwide; however, the underlying mechanisms involved in V...
Autores principales: | Yeh, Yu-Wen, Cheng, Ching-Chia, Yang, Shu-Ting, Tseng, Chi-Feng, Chang, Ting-Yu, Tsai, Sin-Ying, Fu, Earl, Chiang, Chien-Ping, Liao, Li-Chuan, Tsai, Pei-Wen, Yu, Yung-Luen, Su, Jen-Liang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354933/ https://www.ncbi.nlm.nih.gov/pubmed/27901498 http://dx.doi.org/10.18632/oncotarget.13629 |
Ejemplares similares
-
The Role of the VEGF-C/VEGFRs Axis in Tumor Progression and Therapy
por: Chen, Jui-Chieh, et al.
Publicado: (2012) -
Oestrogen-induced angiogenesis promotes adenomyosis by activating the Slug-VEGF axis in endometrial epithelial cells
por: Huang, Tze-Sing, et al.
Publicado: (2014) -
The VEGF/VEGFR Axis Revisited: Implications for Cancer Therapy
por: Mabeta, Peace, et al.
Publicado: (2022) -
Association between EGFR/KRAS mutation and expression of VEGFA, VEGFR and VEGFR2 in lung adenocarcinoma
por: Yuan, Xiao-Han, et al.
Publicado: (2018) -
Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis
por: Hultgren, Nan W., et al.
Publicado: (2020)