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Spleen cells from young but not old immunized mice eradicate large established cancers
PURPOSE: Solid tumors that have grown two weeks or longer in mice and have diameters larger than 1 cm are histologically indistinguishable from autochthonous human cancers. When experimental tumors reach this clinically relevant size, they are usually refractory to most immunotherapies but may be de...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354938/ https://www.ncbi.nlm.nih.gov/pubmed/22415314 http://dx.doi.org/10.1158/1078-0432.CCR-12-0127 |