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Δ40p53 is involved in the inactivation of autophagy and contributes to inhibition of cell death in HCT116-Δ40p53 cells

Δ40p53 is an isoform of wild-type p53 (wtp53). Here, we assessed whether Δ40p53 has the same functions as wild-type p53 in the regulation of cell death and autophagy. First, we used HCT116 (p53+/+) and H1299 (p53-free) cells to produce two cell lines (HCT116-Δ40p53 and H1299-Δ40p53) that express exo...

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Detalles Bibliográficos
Autores principales: Zang, Yunjin, Shi, Ying, Liu, Kai, Qiao, Luxin, Guo, Xianghua, Chen, Dexi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355051/
https://www.ncbi.nlm.nih.gov/pubmed/28061446
http://dx.doi.org/10.18632/oncotarget.14460