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MHY1485 ameliorates UV-induced skin cell damages via activating mTOR-Nrf2 signaling

Ultra Violet (UV)-caused skin cell damage is a main cause of skin cancer. Here, we studied the activity of MHY1485, a mTOR activator, in UV-treated skin cells. In primary human skin keratinocytes, HaCaT keratinocytes and human skin fibroblasts, MHY1485 ameliorated UV-induced cell death and apoptosis...

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Detalles Bibliográficos
Autores principales:	Yang, Bo, Xu, Qiu-Yun, Guo, Chun-Yan, Huang, Jin-Wen, Wang, Shu-Mei, Li, Yong-Mei, Tu, Ying, He, Li, Bi, Zhi-Gang, Ji, Chao, Cheng, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355053/ https://www.ncbi.nlm.nih.gov/pubmed/28061443 http://dx.doi.org/10.18632/oncotarget.14299

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