The IgH locus 3′ cis-regulatory super-enhancer co-opts AID for allelic transvection

Immunoglobulin heavy chain (IgH) alleles have ambivalent relationships: they feature both allelic exclusion, ensuring monoallelic expression of a single immunoglobulin (Ig) allele, and frequent inter-allelic class-switch recombination (CSR) reassembling genes from both alleles. The IgH locus 3′ regu...

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Detalles Bibliográficos
Autores principales: Le Noir, Sandrine, Laffleur, Brice, Carrion, Claire, Garot, Armand, Lecardeur, Sandrine, Pinaud, Eric, Denizot, Yves, Skok, Jane, Cogné, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355067/
https://www.ncbi.nlm.nih.gov/pubmed/28088785
http://dx.doi.org/10.18632/oncotarget.14585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355067/
https://www.ncbi.nlm.nih.gov/pubmed/28088785
http://dx.doi.org/10.18632/oncotarget.14585

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