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The IgH locus 3′ cis-regulatory super-enhancer co-opts AID for allelic transvection
Immunoglobulin heavy chain (IgH) alleles have ambivalent relationships: they feature both allelic exclusion, ensuring monoallelic expression of a single immunoglobulin (Ig) allele, and frequent inter-allelic class-switch recombination (CSR) reassembling genes from both alleles. The IgH locus 3′ regu...
Autores principales: | Le Noir, Sandrine, Laffleur, Brice, Carrion, Claire, Garot, Armand, Lecardeur, Sandrine, Pinaud, Eric, Denizot, Yves, Skok, Jane, Cogné, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355067/ https://www.ncbi.nlm.nih.gov/pubmed/28088785 http://dx.doi.org/10.18632/oncotarget.14585 |
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