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Analysis of molecular mechanisms of 5-fluorouracil-induced steatosis and inflammation in vitro and in mice
Chemotherapy-associated steatohepatitis is attracting increasing attention because it heralds an increased risk of morbidity and mortality in patients undergoing surgery because of liver metastases. The aim of this study was to develop in vitro and in vivo models to analyze the pathogenesis of 5-flu...
Autores principales: | Sommer, Judith, Mahli, Abdo, Freese, Kim, Schiergens, Tobias S., Kuecuekoktay, Fulya Suzan, Teufel, Andreas, Thasler, Wolfgang E., Müller, Martina, Bosserhoff, Anja K., Hellerbrand, Claus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355077/ https://www.ncbi.nlm.nih.gov/pubmed/28055957 http://dx.doi.org/10.18632/oncotarget.14371 |
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