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Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway
Human THUMP domain-containing protein 1 (THUMPD1) is a specific adaptor protein that modulates tRNA acetylation through interaction with NAT10. Immunohistochemical analysis of 146 breast cancer specimens (82 triple-negative and 64 non-triple-negative cases) indicated THUMPD1 expression is higher in...
Autores principales: | Zhang, Xiupeng, Jiang, Guiyang, Sun, Mingfang, Zhou, Haijing, Miao, Yuan, Liang, Mengyuan, Wang, Enhua, Zhang, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355103/ https://www.ncbi.nlm.nih.gov/pubmed/28076326 http://dx.doi.org/10.18632/oncotarget.14528 |
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