Cargando…
EZH2 inhibition suppresses endometrial cancer progression via miR-361/Twist axis
EZH2 inhibition and reactivation of tumor suppressor microRNAs (miRNAs) represent attractive anti-cancer therapeutic strategies. We found that EZH2-suppressed let 7b and miR-361, two likely tumor suppressors, inhibited endometrial cancer (EC) cell proliferation and invasion, and abrogated cancer ste...
Autores principales: | Ihira, Kei, Dong, Peixin, Xiong, Ying, Watari, Hidemichi, Konno, Yosuke, Hanley, Sharon JB, Noguchi, Masayuki, Hirata, Noriyuki, Suizu, Futoshi, Yamada, Takahiro, Kudo, Masataka, Sakuragi, Noriaki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355116/ https://www.ncbi.nlm.nih.gov/pubmed/28088786 http://dx.doi.org/10.18632/oncotarget.14586 |
Ejemplares similares
-
Suppression of iASPP-dependent aggressiveness in cervical cancer through reversal of methylation silencing of microRNA-124
por: Dong, Peixin, et al.
Publicado: (2016) -
MicroRNA-101 targets EZH2, MCL-1 and FOS to suppress proliferation, invasion and stem cell-like phenotype of aggressive endometrial cancer cells
por: Konno, Yosuke, et al.
Publicado: (2014) -
MiR-137 and miR-34a directly target Snail and inhibit EMT, invasion and sphere-forming ability of ovarian cancer cells
por: Dong, Peixin, et al.
Publicado: (2016) -
Reactivating p53 functions by suppressing its novel inhibitor iASPP: a potential therapeutic opportunity in p53 wild-type tumors
por: Dong, Peixin, et al.
Publicado: (2015) -
Reactivation of epigenetically silenced miR-124 reverses the epithelial-to-mesenchymal transition and inhibits invasion in endometrial cancer cells via the direct repression of IQGAP1 expression
por: Dong, Peixin, et al.
Publicado: (2016)