CTLA-4 positive breast cancer cells suppress dendritic cells maturation and function

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), a potent immunoregulatory molecule, can down-regulate T-cell activation and inhibit anti-tumor immune response. This study showed that LPS-stimulated human dendritic cells (DCs) decreased the expression of HLA-DR, CD83 and costimulatory molecules...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Shao, Qianqian, Hao, Shengnan, Zhao, Zhonghua, Wang, Yang, Guo, Xiaofan, He, Ying, Gao, Wenjuan, Mao, Haiting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355131/
https://www.ncbi.nlm.nih.gov/pubmed/28099147
http://dx.doi.org/10.18632/oncotarget.14626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355131/
https://www.ncbi.nlm.nih.gov/pubmed/28099147
http://dx.doi.org/10.18632/oncotarget.14626

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