Cargando…

Vitamin K epoxide reductase regulation of androgen receptor activity

Long-term use of warfarin has been shown to be associated with a reduced risk of prostate cancer. Warfarin belongs to the vitamin K antagonist class of anticoagulants, which inhibit vitamin K epoxide reductase (VKOR). The vitamin K cycle is primarily known for its role in γ-carboxylation, a rare pos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tew, Ben Yi, Hong, Teresa B., Otto-Duessel, Maya, Elix, Catherine, Castro, Egbert, He, Miaoling, Wu, Xiwei, Pal, Sumanta K., Kalkum, Markus, Jones, Jeremy O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355141/ https://www.ncbi.nlm.nih.gov/pubmed/28099154 http://dx.doi.org/10.18632/oncotarget.14639

Ejemplares similares

Identification of neuron selective androgen receptor inhibitors
por: Otto-Duessel, Maya, et al.
Publicado: (2017)

Structure of a bacterial homolog of vitamin K epoxide reductase
por: Li, Weikai, et al.
Publicado: (2010)

Androgen Receptor and PI3K Pathway Activity in Ovarian Cancer
por: Hill, Addie, et al.
Publicado: (2019)

Human Vitamin K Epoxide Reductase as a Target of Its Redox Protein
por: Ledoux, Julie, et al.
Publicado: (2022)

Mechanistic Investigation of the Androgen Receptor DNA-Binding Domain Inhibitor Pyrvinium
por: Pal, Sumanta K., et al.
Publicado: (2019)

Vitamin K epoxide reductase and its paralogous enzyme have different structures and functions
por: Sinhadri, Balaji Chandra Sekhar, et al.
Publicado: (2017)

Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer
por: Liu, Shixuan, et al.
Publicado: (2014)

Vitamin K epoxide reductase contributes to protein disulfide formation and redox homeostasis within the endoplasmic reticulum
por: Rutkevich, Lori A., et al.
Publicado: (2012)

Vitamin K epoxide reductase complex subunit 1 (Vkorc1) haplotype diversity in mouse priority strains
por: Song, Ying, et al.
Publicado: (2008)

Genetic variation and haplotype structure of the gene Vitamin K epoxide reductase complex, subunit 1 in the Tamilian population
por: Kumar, Dhakchinamoorthi Krishna, et al.
Publicado: (2013)

New Insights on Vitamin K Metabolism in Senegalese sole (Solea senegalensis) Based on Ontogenetic and Tissue-Specific Vitamin K Epoxide Reductase Molecular Data
por: Beato, Silvia, et al.
Publicado: (2020)

The role of peroxisome proliferator-activated receptor gamma in prostate cancer
por: Elix, Catherine, et al.
Publicado: (2018)

Mediterranean Diet Decreases the Initiation of Use of Vitamin K Epoxide Reductase Inhibitors and Their Associated Cardiovascular Risk: A Randomized Controlled Trial
por: Castro-Barquero, Sara, et al.
Publicado: (2020)

Effect of Vitamin K Epoxide Reductase Complex 1 Polymorphism on Warfarin Dose Requirement among Patients in Tertiary Care Hospital
por: Veeregowda, Sahana Hadihalli, et al.
Publicado: (2020)

Comparison of two reducing agents dithiothreitol and tris(3-hydroxypropyl)phosphine for in vitro kinetic assay of vitamin K epoxide reductase
por: Takeda, Kazuki, et al.
Publicado: (2020)

VKORC1 and VKORC1L1: Why do Vertebrates Have Two Vitamin K 2,3-Epoxide Reductases?
por: Oldenburg, Johannes, et al.
Publicado: (2015)

Vitamin K epoxide reductase complex subunit 1 (VKORC1) gene polymorphism as determinant of differences in Covid-19-related disease severity
por: Janssen, Rob, et al.
Publicado: (2020)

Phylogeny of the Vitamin K 2,3-Epoxide Reductase (VKOR) Family and Evolutionary Relationship to the Disulfide Bond Formation Protein B (DsbB) Family
por: Bevans, Carville G., et al.
Publicado: (2015)

Is there any association between osteoporotic vertebral fracture and vitamin K epoxide reductase complex subunit-1 polymorphism in Turkish society? A pilot study
por: Ozgen, Merih, et al.
Publicado: (2019)

The catalytic mechanism of vitamin K epoxide reduction in a cellular environment
por: Shen, Guomin, et al.
Publicado: (2020)

Inter and intra ethnic variation of vitamin K epoxide reductase complex and cytochrome P450 4F2 genetic polymorphisms and their prevalence in South Indian population
por: Kumar, Dhakchinamoorthi Krishna, et al.
Publicado: (2013)

Pharmacological effects of a vitamin K(1) 2,3-epoxide reductase (VKOR) inhibitor, 3-acetyl-5-methyltetronic acid, on cisplatin-induced fibrosis in rats
por: UCHIDA, Masashi, et al.
Publicado: (2017)

Factors that influence the androgen receptor cistrome in benign and malignant prostate cells
por: Copeland, Ben T., et al.
Publicado: (2019)

New insights into the catalytic mechanism of vitamin K epoxide reductase (VKORC1) – The catalytic properties of the major mutations of rVKORC1 explain the biological cost associated to mutations()
por: Matagrin, Benjamin, et al.
Publicado: (2013)

Vitamin K Epoxide Reductase Complex Subunit 1-Like 1 (VKORC1L1) Inhibition Induces a Proliferative and Pro-inflammatory Vascular Smooth Muscle Cell Phenotype
por: Aksoy, Adem, et al.
Publicado: (2021)

Differences of adrenal‐derived androgens in 5α‐reductase deficiency versus androgen insensitivity syndrome
por: Han, Bing, et al.
Publicado: (2021)

Cytochrome P450 (CYP2C9*2,*3) & vitamin-K epoxide reductase complex (VKORC1 -1639G<A) gene polymorphisms & their effect on acenocoumarol dose in patients with mechanical heart valve replacement
por: Kaur, Anupriya, et al.
Publicado: (2013)

Electron Transfer Control of Reductase versus Monooxygenase: Catalytic C–H Bond Hydroxylation and Alkene Epoxidation by Molecular Oxygen
por: Mukherjee, Manjistha, et al.
Publicado: (2019)

Epoxide resins
por: Potter, W G
Publicado: (1970)

Epoxides and their derivatives
por: Malinovskii, M S
Publicado: (1965)

Bioengineered polyester nanoparticles for the synergistic treatment of androgenic alopecia via the suppression of 5α-reductase and knockdown of androgen receptor
por: Chen, Xiangru, et al.
Publicado: (2022)

A Practical Guide to Relugolix: Early Experience With Oral Androgen Deprivation Therapy
por: Kasparian, Saro, et al.
Publicado: (2023)

Catalytic developments in the epoxidation of vegetable oils and the analysis methods of epoxidized products
por: Wai, Phyu Thin, et al.
Publicado: (2019)

Impact of diabetes on male sexual function in streptozotocin-induced diabetic rats: Protective role of soluble epoxide hydrolase inhibitor
por: Minaz, Nathani, et al.
Publicado: (2019)

Regio‐ and Stereoselective Epoxidation and Acidic Epoxide Opening of Antibacterial and Antiplasmodial Chlorotonils Yield Highly Potent Derivatives
por: Hofer, Walter, et al.
Publicado: (2022)

Vitamin K1 prevents diabetic cataract by inhibiting lens aldose reductase 2 (ALR2) activity
por: Thiagarajan, R., et al.
Publicado: (2019)

Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride
por: Xiao, Qingpin, et al.
Publicado: (2020)

Structure of human steroid 5α-reductase 2 with anti-androgen drug finasteride
por: Xiao, Qingpin, et al.
Publicado: (2020)

Effects of Androgen Treatment on Growth in Patients with 5-α-Reductase Type 2 Deficiency
por: Lee, Hae In, et al.
Publicado: (2023)

Hydroxy-epoxide and keto-epoxide derivatives of linoleic acid activate trigeminal neurons
por: Doolen, Suzanne, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_eb7is8j7aqglerpv9bdjcpaqnt