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Wilms' tumor gene 1 silencing inhibits proliferation of human osteosarcoma MG-63 cell line by cell cycle arrest and apoptosis activation
Wilms’ tumor gene 1 (WT1) plays complex roles in tumorigenesis, acting as tumor suppressor gene or an oncogene depending on the cellular context. A high WT1 expression level was described in various types of human bone and soft-tissue sarcomas, including osteosarcoma (OS), but its function in carcin...
Autores principales: | Graziano, Adriana Carol Eleonora, Cardile, Venera, Avola, Rosanna, Vicario, Nunzio, Parenti, Carmela, Salvatorelli, Lucia, Magro, Gaetano, Parenti, Rosalba |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355150/ https://www.ncbi.nlm.nih.gov/pubmed/28107196 http://dx.doi.org/10.18632/oncotarget.14715 |
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