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Sensitization of glycoengineered interferon-β1a-resistant cancer cells by cFLIP inhibition for enhanced anti-cancer therapy
In this study, we examined the molecular mechanism underlying the resistance of cancer cells to R27T, a glycoengineered version of recombinant human interferon (IFN)-β1a, and sought to overcome R27T resistance through combination therapy. R27T has been shown to induce anti-proliferation and apoptosi...
Autores principales: | Kim, Tae-Eun, Hong, Sungyoul, Song, Kyoung, Park, Sang-Ho, Shin, Young Kee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355153/ https://www.ncbi.nlm.nih.gov/pubmed/28086218 http://dx.doi.org/10.18632/oncotarget.14573 |
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