Pre-treatment assay of 5-fluorouracil degradation rate (5-FUDR) to improve prediction of 5-fluorouracil toxicity in gastro-esophageal cancer

BACKGROUND: 5-fluorouracil (5-FU) based chemotherapy is the most common first line regimen used in gastric and gastroesophageal junction cancer, but development of severe toxicity is a main concern in the treatment. The present study is aimed to evaluate a novel pre-treatment assay, known as the 5-F...

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Detalles Bibliográficos
Autores principales: Borro, Marina, Botticelli, Andrea, Mazzuca, Federica, Onesti, Elisa Concetta, Gentile, Giovanna, Romiti, Adriana, Cerbelli, Bruna, Mazzotti, Eva, Marchetti, Luca, Lionetto, Luana, Simmaco, Maurizio, Marchetti, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Clinical Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355161/
https://www.ncbi.nlm.nih.gov/pubmed/27738344
http://dx.doi.org/10.18632/oncotarget.12571

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