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Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells

Various signaling pathways exert critical roles in the epithelial to mesenchymal transition (EMT) and cancer stem cells (CSCs). The Wnt/beta-catenin, PI3K/PTEN/Akt/mTORC, Ras/Raf/MEK/ERK, hedgehog (Hh), Notch and TP53 pathways elicit essential regulatory influences on cancer initiation, EMT and prog...

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Detalles Bibliográficos
Autores principales:	McCubrey, James A., Fitzgerald, Timothy L., Yang, Li V., Lertpiriyapong, Kvin, Steelman, Linda S., Abrams, Stephen L., Montalto, Giuseppe, Cervello, Melchiorre, Neri, Luca M., Cocco, Lucio, Martelli, Alberto M., Laidler, Piotr, Dulińska-Litewka, Joanna, Rakus, Dariusz, Gizak, Agnieszka, Nicoletti, Ferdinando, Falzone, Luca, Candido, Saverio, Libra, Massimo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355173/ https://www.ncbi.nlm.nih.gov/pubmed/27999207 http://dx.doi.org/10.18632/oncotarget.13991

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