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Burden of influenza infection in hospitalised children below 6 months of age and above in Hong Kong from 2005 to 2011()
The World Health Organization recommends vaccination of pregnant women for seasonal influenza that can also protect infants aged below 6 months. We estimated incidence and disease burden of influenza in hospitalised children below and above 6 months of age in Hong Kong during a 6 year period. Discha...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier Ltd.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355210/ https://www.ncbi.nlm.nih.gov/pubmed/24837762 http://dx.doi.org/10.1016/j.vaccine.2014.04.063 |
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author | Nelson, E. Anthony S. Ip, Margaret Tam, John S. Mounts, Anthony W. Chau, Sze Lok Law, Shu Kei Goggins, William Simpson, Lucy A. Chan, Paul K.S. |
author_facet | Nelson, E. Anthony S. Ip, Margaret Tam, John S. Mounts, Anthony W. Chau, Sze Lok Law, Shu Kei Goggins, William Simpson, Lucy A. Chan, Paul K.S. |
author_sort | Nelson, E. Anthony S. |
collection | PubMed |
description | The World Health Organization recommends vaccination of pregnant women for seasonal influenza that can also protect infants aged below 6 months. We estimated incidence and disease burden of influenza in hospitalised children below and above 6 months of age in Hong Kong during a 6 year period. Discharge diagnoses for all admissions to public Hong Kong Hospital Authority hospitals, recorded in a central computerised database (Clinical Management System, CMS), were analysed for the period April 2005 to March 2011. Incidence estimates of influenza disease by age group were derived from CMS ICD codes 487–487.99. Laboratory-confirmed influenza infections from a single surveillance hospital were then linked to the CMS entries to assess possible over- and under-diagnosis of influenza based on CMS codes alone. Influenza was recorded as any primary or any secondary diagnosis in 1.3% (1158/86,582) of infants aged above 6 days to below 6 months and 4.3% (20,230/471,482) of children above 6 days to below 18 years. The unadjusted incidence rates per 100,000 person-years based on any CMS diagnosis of influenza in all admission to Hong Kong public hospitals were 627 in the below 2 months of age group and 1762 in the 2 month to below 6 month group. Incidence of hospitalisation for influenza in children was highest from 2 months to below 6 months. In the absence of vaccines for children below 6 months of age, effective vaccination of pregnant women may have a significant impact on reducing influenza hospitalisations in this age group. |
format | Online Article Text |
id | pubmed-5355210 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | The Authors. Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-53552102017-03-24 Burden of influenza infection in hospitalised children below 6 months of age and above in Hong Kong from 2005 to 2011() Nelson, E. Anthony S. Ip, Margaret Tam, John S. Mounts, Anthony W. Chau, Sze Lok Law, Shu Kei Goggins, William Simpson, Lucy A. Chan, Paul K.S. Vaccine Article The World Health Organization recommends vaccination of pregnant women for seasonal influenza that can also protect infants aged below 6 months. We estimated incidence and disease burden of influenza in hospitalised children below and above 6 months of age in Hong Kong during a 6 year period. Discharge diagnoses for all admissions to public Hong Kong Hospital Authority hospitals, recorded in a central computerised database (Clinical Management System, CMS), were analysed for the period April 2005 to March 2011. Incidence estimates of influenza disease by age group were derived from CMS ICD codes 487–487.99. Laboratory-confirmed influenza infections from a single surveillance hospital were then linked to the CMS entries to assess possible over- and under-diagnosis of influenza based on CMS codes alone. Influenza was recorded as any primary or any secondary diagnosis in 1.3% (1158/86,582) of infants aged above 6 days to below 6 months and 4.3% (20,230/471,482) of children above 6 days to below 18 years. The unadjusted incidence rates per 100,000 person-years based on any CMS diagnosis of influenza in all admission to Hong Kong public hospitals were 627 in the below 2 months of age group and 1762 in the 2 month to below 6 month group. Incidence of hospitalisation for influenza in children was highest from 2 months to below 6 months. In the absence of vaccines for children below 6 months of age, effective vaccination of pregnant women may have a significant impact on reducing influenza hospitalisations in this age group. The Authors. Published by Elsevier Ltd. 2014-11-20 2014-05-14 /pmc/articles/PMC5355210/ /pubmed/24837762 http://dx.doi.org/10.1016/j.vaccine.2014.04.063 Text en © 2014 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Nelson, E. Anthony S. Ip, Margaret Tam, John S. Mounts, Anthony W. Chau, Sze Lok Law, Shu Kei Goggins, William Simpson, Lucy A. Chan, Paul K.S. Burden of influenza infection in hospitalised children below 6 months of age and above in Hong Kong from 2005 to 2011() |
title | Burden of influenza infection in hospitalised children below 6 months of age and above in Hong Kong from 2005 to 2011() |
title_full | Burden of influenza infection in hospitalised children below 6 months of age and above in Hong Kong from 2005 to 2011() |
title_fullStr | Burden of influenza infection in hospitalised children below 6 months of age and above in Hong Kong from 2005 to 2011() |
title_full_unstemmed | Burden of influenza infection in hospitalised children below 6 months of age and above in Hong Kong from 2005 to 2011() |
title_short | Burden of influenza infection in hospitalised children below 6 months of age and above in Hong Kong from 2005 to 2011() |
title_sort | burden of influenza infection in hospitalised children below 6 months of age and above in hong kong from 2005 to 2011() |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355210/ https://www.ncbi.nlm.nih.gov/pubmed/24837762 http://dx.doi.org/10.1016/j.vaccine.2014.04.063 |
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