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Gadd45a deficiency accelerates BCR-ABL driven chronic myelogenous leukemia
The Gadd45a stress sensor gene is a member in the Gadd45 family of genes that includes Gadd45b & Gadd45g. To investigate the effect of GADD45A in the development of CML, syngeneic wild type lethally irradiated mice were reconstituted with either wild type or Gadd45a null myeloid progenitors tran...
Autores principales: | Mukherjee, Kaushiki, Sha, Xiaojin, Magimaidas, Andrew, Maifrede, Silvia, Skorski, Tomasz, Bhatia, Ravi, Hoffman, Barbara, Liebermann, Dan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355225/ https://www.ncbi.nlm.nih.gov/pubmed/28086219 http://dx.doi.org/10.18632/oncotarget.14580 |
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