Cargando…

A neutralized human LMP1-IgG inhibits ENKTL growth by suppressing the JAK3/STAT3 signaling pathway

Latent membrane protein 1 (LMP1), which is associated with the development of different types of Epstein-Barr virus (EBV) related lymphoma, has been suggested to be an important oncoprotein. In this study, a human anti-LMP1 IgG antibody (LMP1-IgG) was constructed and characterized by ELISA, western...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mao, Yuan, Wang, Jun, Zhang, Mingzhi, Fan, Weifei, Tang, Qi, Xiong, Siping, Tang, Xiaojun, Xu, Juqing, Wang, Lin, Yang, Shu, Liu, Suyao, Xu, Li, Chen, Yan, Xu, Lin, Yin, Rong, Zhu, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355237/ https://www.ncbi.nlm.nih.gov/pubmed/28009988 http://dx.doi.org/10.18632/oncotarget.14032

Ejemplares similares

LMP1 and LMP2A are potential prognostic markers of extranodal NK/T-cell lymphoma, nasal type (ENKTL)
por: Mao, Yuan, et al.
Publicado: (2012)

JAK-STAT3 and somatic cell reprogramming
por: Tang, Yong, et al.
Publicado: (2013)

Primary pulmonary extranodal natural killer/T-cell lymphoma (ENKTL), nasal type: Two case reports and literature review
por: Hu, Qun, et al.
Publicado: (2020)

The prognostic value of COL3A1/FBN1/COL5A2/SPARC-mir-29a-3p-H19 associated ceRNA network in Gastric Cancer through bioinformatic exploration
por: Shen, Hongyu, et al.
Publicado: (2020)

Subclasses of allergen-specific IgG: Serum IgG2 and IgG3 levels are not predicted by IgG1/IgG4 levels
por: MacGlashan, Donald, et al.
Publicado: (2021)

MiR-375 mitigates retinal angiogenesis by depressing the JAK2/STAT3 pathway
por: Gong, Ruowen, et al.
Publicado: (2022)

The Interaction Between Autophagy and JAK/STAT3 Signaling Pathway in Tumors
por: Xu, Jiangyan, et al.
Publicado: (2022)

Epileptic Neurons Know JAK/STAT3
por: Kumari, Shikha, et al.
Publicado: (2023)

T cells expressing a LMP1-specific chimeric antigen receptor mediate antitumor effects against LMP1-positive nasopharyngeal carcinoma cells in vitro and in vivo
por: Tang, Xiaojun, et al.
Publicado: (2014)

Atractylenolide I Induces Apoptosis and Suppresses Glycolysis by Blocking the JAK2/STAT3 Signaling Pathway in Colorectal Cancer Cells
por: Li, Yanxi, et al.
Publicado: (2020)

Progenitor expansion in apc mutants is mediated by Jak/Stat signaling
por: Lin, Junji, et al.
Publicado: (2011)

IgG3 and IgM Identified as Key to SARS-CoV-2 Neutralization in Convalescent Plasma Pools
por: Kober, Christina, et al.
Publicado: (2022)

JAK/STAT3 and Smad3 activities are required for the wound healing properties of Periplaneta americana extracts
por: Song, Qin, et al.
Publicado: (2017)

Favorable prognostic role of IL-26 in HCC patients associated with JAK-STAT3-dependent autophagy
por: Zhao, Qihong, et al.
Publicado: (2021)

Transport of neutral IgG2 versus anionic IgG4 in PD: implications on the electrokinetic model
por: Pletinck, Anneleen, et al.
Publicado: (2018)

Expression of JAK3, STAT2, STAT4, and STAT6 in pemphigus vulgaris
por: Juczynska, K., et al.
Publicado: (2020)

An inhibitor of cholesterol absorption displays anti-myeloma activity by targeting the JAK2-STAT3 signaling pathway
por: Xu, Xin, et al.
Publicado: (2016)

The Expression of IgG and IgG4 in Orbital MALT Lymphoma: The Similarities and Differences of IgG4-Related Diseases
por: Li, Kai-Ming, et al.
Publicado: (2020)

Targeting the tumor microenvironment: JAK-STAT3 signaling
por: Bournazou, Eirini, et al.
Publicado: (2013)

IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody
por: Richardson, Simone I., et al.
Publicado: (2019)

HIV Broadly Neutralizing Antibodies Expressed as IgG3 Preserve Neutralization Potency and Show Improved Fc Effector Function
por: Richardson, Simone I., et al.
Publicado: (2021)

JAK/STAT signaling in hepatocellular carcinoma
por: Hin Tang, Justin Jit, et al.
Publicado: (2020)

Membranoproliferative glomerulonephritis with predominant IgG2 and IgG3 deposition in a patient with IgG4-related disease
por: Ueki, Kenji, et al.
Publicado: (2015)

MYCL promotes the progression of triple-negative breast cancer by activating the JAK/STAT3 pathway
por: Jiang, Hongnan, et al.
Publicado: (2022)

JAK/STAT Pathway Mutations in T-ALL, Including the STAT5B N642H Mutation, are Sensitive to JAK1/JAK3 Inhibitors
por: Govaerts, Inge, et al.
Publicado: (2019)

Correlation between the IgG/IgA Antibody Response against PEDV Structural Protein and Virus Neutralization
por: Song, Xu, et al.
Publicado: (2023)

Mechanisms of chronic JAK-STAT3-SOCS3 signaling in obesity
por: Wunderlich, Claudia M., et al.
Publicado: (2013)

Epstein-Barr Virus encoded LMP1 regulates cyclin D1 promoter activity by nuclear EGFR and STAT3 in CNE1 cells
por: Xu, Yang, et al.
Publicado: (2013)

Xuanfei Baidu Decoction suppresses complement overactivation and ameliorates IgG immune complex-induced acute lung injury by inhibiting JAK2/STAT3/SOCS3 and NF-κB signaling pathway
por: Li, Caixia, et al.
Publicado: (2023)

VSIG4 Silencing Inhibits Glioblastoma Growth by Regulating the JAK2/STAT3 Pathway
por: Zheng, Congying, et al.
Publicado: (2023)

Co-Inhibition of the Immunoproteasome Subunits LMP2 and LMP7 Ameliorates Immune Thrombocytopenia
por: Du, Sheng-hong, et al.
Publicado: (2021)

Development of new prognostic model based on pretreatment βLRI and LLRI for stage IE/IIE upper aerodigestive tract ENKTL, nasal type
por: Dai, Wumin, et al.
Publicado: (2017)

Autocrine Production of Interleukin-34 Promotes the Development of Endometriosis through CSF1R/JAK3/STAT6 signaling
por: Lin, Kaiqing, et al.
Publicado: (2019)

The Interaction of the IFNγ/JAK/STAT1 and JAK/STAT3 Signalling Pathways in EGFR-Mutated Lung Adenocarcinoma Cells
por: Han, Yaguang, et al.
Publicado: (2022)

Activation of EHF via STAT3 phosphorylation by LMP2A in Epstein‐Barr virus–positive gastric cancer
por: Li, Wenzhe, et al.
Publicado: (2021)

Increased expression of hepcidin and associated upregulation of JAK/STAT3 signaling in human gastric cancer
por: Zuo, Erdong, et al.
Publicado: (2018)

IgG3 collaborates with IgG1 and IgA to recruit effector function in RV144 vaccinees
por: Fischinger, Stephanie, et al.
Publicado: (2020)

MicroRNA-141-3p inhibits the progression of oral squamous cell carcinoma via targeting PBX1 through the JAK2/STAT3 pathway
por: Cao, Mingguo, et al.
Publicado: (2022)

Dihydroartemisinin attenuates pulmonary inflammation and fibrosis in rats by suppressing JAK2/STAT3 signaling
por: You, Xiaolan, et al.
Publicado: (2022)

JAK/STAT signaling in diabetic kidney disease
por: Liu, Yingjun, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_nq7obajai6e32frt82vm04a55v