Cargando…

The role of miR-17-92 in the miRegulatory landscape of Ewing sarcoma

MicroRNAs serve to fine-tune gene expression and play an important regulatory role in tissue specific gene networks. The identification and validation of miRNA target genes in a tissue still poses a significant problem since the presence of a seed sequence in the 3′UTR of an mRNA and its expression...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schwentner, Raphaela, Herrero-Martin, David, Kauer, Maximilian O, Mutz, Cornelia N, Katschnig, Anna M, Sienski, Grzegorz, Alonso, Javier, Aryee, Dave NT, Kovar, Heinrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355239/ https://www.ncbi.nlm.nih.gov/pubmed/28030800 http://dx.doi.org/10.18632/oncotarget.14091

Ejemplares similares

EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells
por: Mutz, Cornelia N., et al.
Publicado: (2017)

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers
por: Tsafou, Kalliopi, et al.
Publicado: (2018)

YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells
por: Bierbaumer, Lisa, et al.
Publicado: (2021)

EWS‐FLI1 impairs aryl hydrocarbon receptor activation by blocking tryptophan breakdown via the kynurenine pathway
por: Mutz, Cornelia N., et al.
Publicado: (2016)

EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory feedback in Ewing sarcoma
por: Katschnig, A M, et al.
Publicado: (2017)

Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma
por: Herrero-Martin, David, et al.
Publicado: (2011)

Variability in functional p53 reactivation by PRIMA-1(Met)/APR-246 in Ewing sarcoma
por: Aryee, D N T, et al.
Publicado: (2013)

Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer
por: Bilke, Sven, et al.
Publicado: (2013)

Suppression of FOXO1 is responsible for a growth regulatory repressive transcriptional sub-signature of EWS-FLI1 in Ewing sarcoma
por: Niedan, S, et al.
Publicado: (2014)

A Molecular Function Map of Ewing's Sarcoma
por: Kauer, Maximilian, et al.
Publicado: (2009)

Zooming in on Long Non-Coding RNAs in Ewing Sarcoma Pathogenesis
por: Aryee, Dave N. T., et al.
Publicado: (2022)

Downstream EWS/FLI1 - upstream Ewing's sarcoma
por: Kovar, Heinrich
Publicado: (2010)

The First European Interdisciplinary Ewing Sarcoma Research Summit
por: Kovar, Heinrich, et al.
Publicado: (2012)

EWS-FLI1 employs an E2F switch to drive target gene expression
por: Schwentner, Raphaela, et al.
Publicado: (2015)

CD133 expression in chemo-resistant Ewing sarcoma cells
por: Jiang, Xiaohua, et al.
Publicado: (2010)

Progress in the Molecular Biology of Ewing Tumors
por: Kovar, Heinrich
Publicado: (1998)

Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma
por: Weaver, Davis T., et al.
Publicado: (2021)

An integrated analysis of miRNA and gene copy numbers in xenografts of Ewing's sarcoma
por: Mosakhani, Neda, et al.
Publicado: (2012)

miR-124 represses the mesenchymal features and suppresses metastasis in Ewing sarcoma
por: Li, Yunyun, et al.
Publicado: (2016)

miR-125b develops chemoresistance in Ewing sarcoma/primitive neuroectodermal tumor
por: Iida, Keiichiro, et al.
Publicado: (2013)

Growth-Promoting Role of the miR-106a∼363 Cluster in Ewing Sarcoma
por: Dylla, Layne, et al.
Publicado: (2013)

Cutaneous Ewing Sarcoma and Ewing Sarcoma of the Bone: Distinct Diseases
por: Tavakkoli, Montreh, et al.
Publicado: (2018)

Ewing Sarcoma—Diagnosis, Treatment, Clinical Challenges and Future Perspectives
por: Zöllner, Stefan K., et al.
Publicado: (2021)

Survival is influenced by approaches to local treatment of Ewing sarcoma within an international randomised controlled trial: analysis of EICESS-92
por: Whelan, Jeremy, et al.
Publicado: (2018)

C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells
por: Gardiner, Jamie D., et al.
Publicado: (2017)

Ewing Sarcoma of the Posterior Fossa in an Adolescent Girl
por: Stark, Andreas M., et al.
Publicado: (2014)

Mechanisms, Diagnosis and Treatment of Bone Metastases
por: Ban, Jozef, et al.
Publicado: (2021)

Ewing's sarcoma of zygoma
por: Deshingkar, SA, et al.
Publicado: (2009)

Ewing's sarcoma of the mandible
por: Rao, B. H. Sripathi, et al.
Publicado: (2011)

Chemotherapy in Ewing’s sarcoma
por: Jain, Sandeep, et al.
Publicado: (2010)

The Biology of Ewing Sarcoma
por: Ross, Keir A., et al.
Publicado: (2013)

Ewing's Sarcoma of the Finger
por: Gökalp, Mehmet Ata, et al.
Publicado: (2014)

Ewing's Sarcoma of the Calcaneum
por: Sherif, P Ajmal, et al.
Publicado: (2017)

Paratesticular Ewing's sarcoma
por: Koshevarova, Victoria, et al.
Publicado: (2023)

ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma
por: Srivastava, Swati, et al.
Publicado: (2019)

Ewing Sarcoma and Ewing-Like Sarcoma and the Role of NKX2.2 Immunoreactivity
por: Ullah, Asad, et al.
Publicado: (2021)

Phenotypic Characterization of miR-92a(−/−) Mice Reveals an Important Function of miR-92a in Skeletal Development
por: Penzkofer, Daniela, et al.
Publicado: (2014)

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery
por: Kling, Matthew J., et al.
Publicado: (2020)

Differentially Expressed miRNAs in Ewing Sarcoma Compared to Mesenchymal Stem Cells: Low miR-31 Expression with Effects on Proliferation and Invasion
por: Karnuth, Bianca, et al.
Publicado: (2014)

Insights into Regulation of the miR-17-92 Cluster of miRNAs in Cancer
por: Fuziwara, Cesar Seigi, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_1du7okc5215547jr6pfk307b3a